Neuroinflammation and Immune System Involvement

Neuroinflammation plays a crucial role in Alzheimer’s disease and other dementias by driving neuronal damage and cognitive decline. The immune system's dysregulation, including the activation of microglia and astrocytes, exacerbates neuroinflammatory responses. These processes promote the accumulation of amyloid-beta plaques and tau tangles, pivotal in disease progression. Emerging therapies are targeting neuroinflammation to mitigate these effects. Strategies include modulating microglial activation, reducing pro-inflammatory cytokines, and employing anti-inflammatory agents. By addressing these immunological mechanisms, new treatments aim to slow or reverse neurodegenerative processes, offering hope for improved management and potential reversal of dementia symptoms.

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