Neuroinflammation and Immune Response in Dementia

Neuroinflammation and immune response play a critical role in the pathogenesis of dementia, including Alzheimer's disease and other neurodegenerative disorders. Chronic activation of microglia and astrocytes triggers sustained neuroinflammatory processes, leading to neuronal damage and cognitive decline. The interplay between innate and adaptive immune systems influences amyloid-beta plaque accumulation and tau pathology. Targeting neuroinflammation offers promising therapeutic potential for slowing dementia progression. Understanding immune signaling pathways, cytokine release, and blood-brain barrier dysfunction is essential for developing advanced treatments. This emerging field highlights the importance of neuroimmune modulation in improving patient outcomes and managing dementia effectively.

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